Evolución de la leucemia linfoblástica aguda en la edad pediátrica en 29 años ( )Outcome of acute lymphoblastic leukemia in the pediatric age group . La leucemia linfoblástica aguda (LLA) es el cáncer más común en los niños y está entre los más curables de las malignidades pediátricas. El análisis citogenético de las células blásticas en niños con leucemia linfoblástica aguda (LLA) ha permitido el reconocimiento de alteraciones cromosómicas.
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Cytogenetic analysis of lehcemia cells in childhood acute lymphoblastic leukemia has led to the recognition of specific non-random chromosomal abnormalities with prognostic value.
Most patients with ALL show karyotype abnormalities, either in chromosome number ploidy or as structural changes such as translocations, inversions, or deletions. Many of these chromosomal alterations are associated with specific cytomorphological and immunological types.
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The greatest impact on patient management has been the finding that the cytogenetic result is an independent prognostic indicator. Certain karyotypes are associated with a favorable prognosis while others indicate a poor outcome. This has led to the administration of alternative therapies according to risk.
This study focuses on the most important chromosomal abnormalities found in childhood ALL and their prognostic and therapeutic implications. Cytogenetic abnormalities in acute lymphoblastic leukemia. Hospital 12 de Octubre Edificio Materno-Infantil. Hospital 12 de Octubre. This study focuses on the most important chromosomal abnormalities found in auda ALL and their prognostic and therapeutic implications. Current status of cytogenetic research in childhood acute lymphoblastic leukemia.
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Factores de riesgo para la leucemia linfocítica aguda
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Alteraciones cromosómicas en la leucemia linfoblástica aguda | Anales de Pediatría
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Factores de riesgo para la leucemia linfocítica aguda
Br J Haematol, 90pp. Genes Chromosom Cancer, 9pp. Si continua navegando, consideramos que acepta su uso. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.
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