Definición. Es una forma precoz de cáncer de piel que se encuentra en el pene. El cáncer se denomina carcinoma escamocelular in situ. Este tipo de cáncer se. Article (PDF Available) in Anais Brasileiros de Dermatologia 91(5 Suppl .. Eritroplasia de Queyrat e líquen escleroso e atrófico: associação. A eritroplasia de Queyrat foi originalmente descrita por Tarnovsky em Em , Queyrat, dermatologista parisiense, aplicou o termo “eritroplasia” em.
|Published (Last):||19 December 2006|
|PDF File Size:||7.41 Mb|
|ePub File Size:||8.51 Mb|
|Price:||Free* [*Free Regsitration Required]|
We report a year-old male patient diagnosed with erythroplasia of Queyrat.
Erythroplasia of Queyrat
Despite previous indication of penectomy, he was successfully treated with topical 5-fluorouracil. Erythroplasia of Queyrat EQ is a rare in situ squamous cell carcinoma SCC of the glans penis, which typically appears as one or more well-marginated erythematous velvety plaques.
Predisposing factors include lack of hygiene, smegma, humidity, and heat. Histopathological examination hematoxylin-eosin stain shows identical results to Bowen’s disease. However, the epidemiology and anatomical location of these two conditions are mutually exclusive. Egitroplasia removal of cancer by partial or total penectomy is a standard therapy, but these radical procedures can cause considerable mental eritroplzsia, including suicide.
Therefore, the development of a non-invasive alternative treatment for EQ is essential. We report the case of an EQ patient with penectomy indicated by an urologist, but who responded well to topical treatment with topical 5-fluorouracil.
We report a year-old male patient present to our institution with a history of having performed circumcision for about eight years due to an eroded lesion on the distal glans treated with antibiotics and topical corticosteroids without improvement.
The patient reported that the lesion had been persistent for eight years and had recently increased in size. Local pain and possible bleeding were also reported. The patient had gone through prior consultation with a urologist who suggested radical excision of the tip of the glans.
We observed no inguinal lymphadenopathy. General physical examination was normal. An incisional biopsy showed proliferation of atypical keratinocytes in the epidermis, with perivascular lymphocytic infiltrate in the adjacent dermis compatible with EQ Figure 2.
We obtained a favorable result fifteen days after the application, considering the initial irritation predicted with the use of eritroplazia medication Figure 3. We repeated two more cycles of treatment for two weeks, with an interval of fifteen days between the cycles Figure 4.
Thirty days after the third cycle, the lesion showed complete clinical resolution, displaying only discreet erythema at the distal glans.
Two months after the third cycle, we performed a biopsy that showed standard lichenoid interface dermatitis with no atypical cells in the epidermis Figure 5. Biopsy performed two months after the end of treatment: Thus, we decided to monitor the patient monthly. Six eritroplasua after the treatment, physical examination revealed only a scar in the lesion site Figure 6. One year after the treatment, the patient showed no recurrence, progressing to complete healing and maintaining continuous follow up.
Surgical treatment involving partial or total penectomy should be performed with caution, considering that it is often accompanied by psychological distress, intense emotional distress, and depression.
eritroplasia de Queyrat – English Translation – Word Magic Spanish-English Dictionary
Physicians must assess the degree of cellular atypia to check if it is restricted to the epidermis, differing EQ from invasive SCC. In a review paper on the treatment of EQ, Goette concluded that quyerat therapeutic regimen with 5-fluorouracil is associated with high cure rates without eritroplazia of recurrence.
The drug can be used continuously for weeks and its side effects include erythema, edema, and local irritation. By opting for conservative treatment with 5-fluorouracil, continued and prolonged clinical follow-up is fundamental. The results of every therapeutic step should be monitored and attention should be given to the possible evolution of the lesion to invasive SCC. National Center for Biotechnology InformationU. Journal List An Bras Dermatol v.
Author information Article notes Copyright and License information Disclaimer. Received Mar 28; Accepted May 9.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Penile multifocal superficial carcinoma: Emphasis to toluidine blue test
Abstract We report a year-old male patient diagnosed with erythroplasia of Queyrat. Carcinoma in Situ, Penis, Therapeutics. CASE REPORT We report a year-old male patient present to our institution with a history of having performed circumcision for about eight years due to an eroded lesion on the distal glans treated with antibiotics and topical corticosteroids without improvement.
Open in a separate window. Footnotes Conflict of Interest: Epidermal skin tumours; pp. Carcinoma in situ of the penis. Dahlgren S, Nordenstrom B.
Year book Medical Publishers, Inc; A case of erythroplasia of Queyrat successfully treated with combination ds dioxide laser vaporization and surgery. J Eur Acad Dermatol Venereol. Optical coherence tomography in dermatology: Erythroplasia of Queyrat refractory to photodynamic therapy. Review of erythroplasia of Queyrat and its treatment.