University of Groningen. Bistability, Epigenetics, and Bet-Hedging in Bacteria. Veening, Jan; Smits, Wiep Klaas; Kuipers, Oscar. Published in. Bet-hedging and epigenetic inheritance in bacterial cell development This developmental process is bistable, and only a subpopulation of. Clonal populations of microbial cells often show a high degree of phenotypic variability under homogeneous conditions. Stochastic fluctuations in the cellular.

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Bistability, Epigenetics, and Bet-Hedging in Bacteria – Dimensions

Stochastic fluctuations in the cellular components that determine cellular states can cause two distinct subpopulations, a property called bistability. Phenotypic heterogeneity can be readily obtained by interlinking multiple gene regulatory pathways, effectively resulting in a genetic logic-AND gate.


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Citations Publications citing this paper. Showing of extracted citations. Black and white with some shades of grey: RaoSantosh Koirala Molecular microbiology Culture history and population heterogeneity as determinants of bacterial adaptation: Evolution of microbes and viruses: KooninYuri I.

Bistability, epigenetics, and bet-hedging in bacteria.

Hyperosmotic stress response of Campylobacter jejuni. Gaynor Journal of bacteriology References Publications referenced by this paper.

Showing of references. Time-lapse study that shows that sporulation in B. Provides evidence for the excitable model that dictates competence development.

Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation. Enzyme Induction as an All-or-none Phenomenon.

Bistability and biofilm formation in Bacillus subtilis. Experimental study showing directly for the first time that noise in comK transcription determines entry into the competent state in B.

High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis. Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation.


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